Empowering rural women is one of the policies and strategies used to develop rural businesses because rural businesses can create employment and reduce unemployment, resulting in increased high self-confidence and empowerment of the villagers. Regarding the importance of this issue, the present study aimed at investigating the effect of empowering women on the motivation of creating and developing rural businesses. This paper is an applied study in terms of purpose and descriptive-analytic in nature. The statistical population consists of 504 samples selected from 84 villages in 26 rural districts. The data collected using bibliographic and field study methods. Analyzing data, a compiled framework based on the previous studies was used, which was composed on 5 indexes of empowerment in 50 items and rural business in 14 items. The results showed that empowering women in making them motivated to create and develop rural businesses was effective as the result of multivariate regression indicated that the empowerment variables account for .378 of changes in rural businesses. The results of the KODAS technique used to assess the motivation of women to develop rural businesses show that rural women are in different business motivation situations, so that only women in Sarchaqa and Seyed Ayaz was more favorable than other villages.